Role of astrocytes in the regulation of synaptic transmission by endocannabinoids. The canonical mechanism by which ECBs regulate synaptic transmission is through retrograde signalling from the post-synaptic neuron to the pre-synaptic terminal.
Feb 27, 2009 · Astrocytes process synaptic information - Volume 4 Issue 1 - Alfonso Araque amounts of evidence obtained by several groups during the past years demonstrated the existence of a bidirectional communication between astrocytes and neurons, which prompted a re-examination of the role of astrocytes in the physiology of the nervous system Structural and Functional Plasticity of Astrocyte ... Sep 17, 2014 · We used an experimental paradigm known to induce astrocyte-mediated synaptic modulation, i.e., endocannabinoids (ECBs) released from depolarized neurons stimulate the astrocyte Ca 2+ signal that leads to a transient enhancement of synaptic efficacy at single CA3–CA1 synapses (2008) Endocannabinoids mediate neuron-astrocyte communication. Neuron–astrocyte communication and synaptic plasticity ... Aug 01, 2010 · Neuron–astrocyte communication and synaptic plasticity Neuron–astrocyte communication and synaptic plasticity Paixão, Sónia; Klein, Rüdiger 2010-08-01 00:00:00 By forming close contacts with synapses, astrocytes secrete neuroactive substances and remove neurotransmitters, thus influencing the processing of information by the nervous system.
In addition, the endocannabinoid system supports neuron-astrocyte communication through CB1R-mediated phospholipase C-dependent Ca 2+ mobilization …
Glutamate‐dependent astrocyte modulation of synaptic ... Glutamate‐dependent astrocyte modulation of synaptic transmission between cultured hippocampal neurons. Pal Anders Floor and Ilangko Balasingham Communication theory aspects of synaptic transmission, (2015) , Endocannabinoids Mediate Neuron-Astrocyte Communication, Neuron, 10.1016/j.neuron.2008.01.029, 57, 6 Cellular/Molecular Neuroscience - Digital CSIC Endocannabinoids and their receptor CB1 play key roles in brain function. Astrocytes express CB1Rs that are activated by endocannabinoids released by neurons.
Recent studies also demonstrate the existence of eCB-mediated neuron-astrocyte communication, supporting the potential role of cannabinoid receptors expressed by glial cells in both physiological and pathological processes (Navarrete and Araque, 2008).
Astrocytes express CB1Rs that are activated by endocannabinoids released by neurons. However, the consequences of the endocannabinoid-mediated neuron-astrocyte signaling on synaptic transmission are unknown. The endocannabinoid system: from the receptors to therapy ... The endocannabinoid system (ECS) received a lot of attention ever since
Astrocytes as Regulators of Synaptic Function: A Quest for ... May 02, 2011 · The emerging role of astrocytes in neural communication represents a conceptual challenge. In striking contrast to the rapid and highly space- and time-constrained machinery of neuronal spike propagation and synaptic release, astroglia appear slow and imprecise. One of the hallmarks of the astrocytic response is the generation of calcium elevations, which further affect downstream cellular processes. Jul 10, 2014 · The pedunculopontine nucleus (PPN) is known as the cholinergic part of the reticular activating system (RAS) and it plays an important role in transitions of slow-wave sleep to REM sleep and wakefulness. Although both exogenous and endocannabinoids affect sleep, the mechanism of endocannabinoid neuromodulation has not been characterized at cellular level in the PPN. In this …
Astrocytes process synaptic information | Neuron Glia ... Feb 27, 2009 · Astrocytes process synaptic information - Volume 4 Issue 1 - Alfonso Araque amounts of evidence obtained by several groups during the past years demonstrated the existence of a bidirectional communication between astrocytes and neurons, which prompted a re-examination of the role of astrocytes in the physiology of the nervous system
Structural and Functional Plasticity of Astrocyte ... Sep 17, 2014 · We used an experimental paradigm known to induce astrocyte-mediated synaptic modulation, i.e., endocannabinoids (ECBs) released from depolarized neurons stimulate the astrocyte Ca 2+ signal that leads to a transient enhancement of synaptic efficacy at single CA3–CA1 synapses (2008) Endocannabinoids mediate neuron-astrocyte communication. Neuron–astrocyte communication and synaptic plasticity ... Aug 01, 2010 · Neuron–astrocyte communication and synaptic plasticity Neuron–astrocyte communication and synaptic plasticity Paixão, Sónia; Klein, Rüdiger 2010-08-01 00:00:00 By forming close contacts with synapses, astrocytes secrete neuroactive substances and remove neurotransmitters, thus influencing the processing of information by the nervous system. User:Tkadm30/Notebook/Endocannabinoids - OpenWetWare
FABPs allosteric communication with dopamine neurotransmitters modulate synaptic plasticity and BDNF-mediated synaptogenesis. Endocannabinoids Mediate Neuron-Astrocyte Communication; Review: Cannabinoid and cannabinoid-like receptors in RA may enhance neuron-astrocyte signaling through activation of retinoid X receptor (RXR/PPAR
Recent Publications
Navarrete M, Araque A (2008) Endocannabinoids mediate neuron-astrocyte communication. Frontiers | Functional Roles of Astrocyte Calcium ... Jan 17, 2018 · Astrocytes are fundamental players in the regulation of synaptic transmission and plasticity. They display unique morphological and phenotypical features that allow to monitor and to dynamically respond to changes. One of the hallmarks of the astrocytic response is the generation of calcium elevations, which further affect downstream cellular processes. Technical advances in the …
Cannabinoid receptors contribute to astroglial Ca2 ... Oct 19, 2014 · Endocannabinoids are lipid messengers that are produced via a complex, Ca 2+-regulated cascade. User:Tkadm30/Notebook/Endocannabinoids - OpenWetWare
FABPs allosteric communication with dopamine neurotransmitters modulate synaptic plasticity and BDNF-mediated synaptogenesis. PY - 2008/3/27. Y1 - 2008/3/27. N2 - Cannabinoid receptors play key roles in brain function, and cannabinoid effects in brain physiology and drug-related behavior are thought to be mediated by receptors present in neurons. Endocannabinoids Mediate Neuron-Astrocyte Communication ... In addition, the endocannabinoid system supports neuron-astrocyte communication through CB1R-mediated phospholipase C-dependent Ca 2+ mobilization …
Endocannabinoids Potentiate Synaptic Transmission through ... Oct 06, 2010 · Endocannabinoids and their receptor CB1 play key roles in brain function. Astrocytes express CB1Rs that are activated by endocannabinoids released by neurons.Abstract